:root {
            --primary: #2c6fbb;
            --secondary: #4a9d48;
            --danger: #e74c3c;
            --warning: #f39c12;
            --light-gray: #f5f5f5;
            --medium-gray: #e0e0e0;
            --dark-gray: #333333;
            --card-shadow: 0 2px 10px rgba(0,0,0,0.1);
        }
        
        * {
            box-sizing: border-box;
            margin: 0;
            padding: 0;
            font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, Oxygen, Ubuntu, Cantarell, 'Open Sans', 'Helvetica Neue', sans-serif;
        }
        
        body {
            background-color: #f8f9fa;
            color: #333;
            line-height: 1.6;
        }
        
        .container {
            max-width: 800px;
            margin: 0 auto;
            padding: 15px;
        }
        
        .view {
            display: none;
            animation: fadeIn 0.3s ease;
        }
        
        .view.active {
            display: block;
        }
        
        @keyframes fadeIn {
            from { opacity: 0; transform: translateY(10px); }
            to { opacity: 1; transform: translateY(0); }
        }
        
        header {
            background-color: white;
            padding: 15px 0;
            box-shadow: 0 2px 5px rgba(0,0,0,0.1);
            position: sticky;
            top: 0;
            z-index: 100;
        }
        
        .header-content {
            display: flex;
            justify-content: space-between;
            align-items: center;
            max-width: 800px;
            margin: 0 auto;
            padding: 0 15px;
        }
        
        .app-title {
            font-size: 1.4rem;
            font-weight: 600;
            color: var(--primary);
        }
        
        .toolbar {
            display: flex;
            gap: 15px;
        }
        
        .toolbar button {
            background: none;
            border: none;
            font-size: 1.2rem;
            color: var(--primary);
            cursor: pointer;
        }
        
        .btn {
            display: inline-block;
            padding: 10px 20px;
            background-color: var(--primary);
            color: white;
            border: none;
            border-radius: 8px;
            font-weight: 500;
            cursor: pointer;
            text-align: center;
            text-decoration: none;
            transition: background-color 0.2s;
        }
        
        .btn:hover {
            background-color: #235a9c;
        }
        
        .btn-secondary {
            background-color: var(--secondary);
        }
        
        .btn-secondary:hover {
            background-color: #3d853b;
        }
        
        .btn-danger {
            background-color: var(--danger);
        }
        
        .btn-danger:hover {
            background-color: #c0392b;
        }
        
        .btn-outline {
            background-color: transparent;
            border: 1px solid var(--primary);
            color: var(--primary);
        }
        
        .btn-outline:hover {
            background-color: rgba(44, 111, 187, 0.1);
        }
        
        .card {
            background-color: white;
            border-radius: 12px;
            padding: 20px;
            margin-bottom: 20px;
            box-shadow: var(--card-shadow);
        }
        
        .section-title {
            font-size: 1.1rem;
            font-weight: 600;
            margin-bottom: 15px;
            color: var(--dark-gray);
            padding-bottom: 8px;
            border-bottom: 1px solid var(--medium-gray);
        }
        
        .form-group {
            margin-bottom: 15px;
        }
        
        .form-group label {
            display: block;
            margin-bottom: 5px;
            font-weight: 500;
        }
        
        .form-control {
            width: 100%;
            padding: 12px;
            border: 1px solid var(--medium-gray);
            border-radius: 8px;
            font-size: 1rem;
        }
        
        .form-control:focus {
            outline: none;
            border-color: var(--primary);
            box-shadow: 0 0 0 2px rgba(44, 111, 187, 0.2);
        }
        
        .detail-row {
            display: flex;
            justify-content: space-between;
            padding: 8px 0;
        }
        
        .detail-row .title {
            font-weight: 500;
        }
        
        .detail-row .value {
            color: #666;
        }
        
        .warning-note {
            background-color: #fff3cd;
            color: #856404;
            padding: 15px;
            border-radius: 8px;
            text-align: center;
            margin: 20px 0;
            font-size: 0.9rem;
            border-left: 4px solid #ffc107;
        }
        
        .calculation-item {
            padding: 15px;
            border-bottom: 1px solid var(--medium-gray);
            cursor: pointer;
            transition: background-color 0.2s;
        }
        
        .calculation-item:hover {
            background-color: var(--light-gray);
        }
        
        .calculation-item h3 {
            font-size: 1.1rem;
            margin-bottom: 5px;
        }
        
        .calculation-item p {
            font-size: 0.9rem;
            color: #666;
        }
        
        .stepper {
            display: flex;
            align-items: center;
            gap: 10px;
        }
        
        .stepper button {
            width: 30px;
            height: 30px;
            border-radius: 50%;
            background-color: var(--primary);
            color: white;
            border: none;
            font-size: 1rem;
            cursor: pointer;
            display: flex;
            align-items: center;
            justify-content: center;
        }
        
        .stepper .count {
            min-width: 30px;
            text-align: center;
        }
        
        .info-box {
            padding: 15px;
            border-radius: 8px;
            margin-bottom: 15px;
            font-size: 0.95rem;
        }
        
        .info-box-primary {
            background-color: rgba(44, 111, 187, 0.1);
            border-left: 4px solid var(--primary);
        }
        
        .info-box-success {
            background-color: rgba(74, 157, 72, 0.1);
            border-left: 4px solid var(--secondary);
        }
        
        .info-box-warning {
            background-color: rgba(243, 156, 18, 0.1);
            border-left: 4px solid var(--warning);
        }
        
        .info-box-danger {
            background-color: rgba(231, 76, 60, 0.1);
            border-left: 4px solid var(--danger);
        }
        
        .info-box-purple {
            background-color: rgba(128, 0, 128, 0.1);
            border-left: 4px solid purple;
        }
        
        .info-box-indigo {
            background-color: rgba(75, 0, 130, 0.1);
            border-left: 4px solid indigo;
        }
        
        .toggle-switch {
            position: relative;
            display: inline-block;
            width: 60px;
            height: 34px;
        }
        
        .toggle-switch input {
            opacity: 0;
            width: 0;
            height: 0;
        }
        
        .toggle-slider {
            position: absolute;
            cursor: pointer;
            top: 0;
            left: 0;
            right: 0;
            bottom: 0;
            background-color: #ccc;
            transition: .4s;
            border-radius: 34px;
        }
        
        .toggle-slider:before {
            position: absolute;
            content: "";
            height: 26px;
            width: 26px;
            left: 4px;
            bottom: 4px;
            background-color: white;
            transition: .4s;
            border-radius: 50%;
        }
        
        input:checked + .toggle-slider {
            background-color: var(--primary);
        }
        
        input:checked + .toggle-slider:before {
            transform: translateX(26px);
        }
        
        .footer-note {
            font-size: 0.8rem;
            color: #666;
            text-align: center;
            padding: 15px;
            margin-top: 20px;
            border-top: 1px solid var(--medium-gray);
        }
        
        .centered-content {
            display: flex;
            flex-direction: column;
            align-items: center;
            justify-content: center;
            min-height: 300px;
            text-align: center;
            color: #666;
        }
        
        .back-button {
            background: none;
            border: none;
            color: var(--primary);
            font-size: 1rem;
            cursor: pointer;
            display: flex;
            align-items: center;
            gap: 5px;
            padding: 5px 0;
        }
        
        .molecule-display {
            font-size: 1.8rem;
            font-weight: bold;
            margin-bottom: 20px;
            text-align: center;
            color: var(--primary);
        }
        
        .prescription-header {
            text-align: center;
            font-weight: bold;
            text-decoration: underline;
            margin-bottom: 15px;
        }
        
        .prescription-item {
            margin-bottom: 8px;
        }
        
        .input-group {
            display: flex;
            align-items: center;
            gap: 10px;
            flex-wrap: wrap;
        }
        
        .input-group .form-control {
            flex: 1;
        }
        
        .final-calculation {
            font-size: 1.2rem;
            font-weight: bold;
            text-align: center;
            margin: 15px 0;
            color: var(--danger);
        }
        
        .navigation-buttons {
            display: flex;
            gap: 10px;
            margin-top: 20px;
        }
        
        .navigation-buttons .btn {
            flex: 1;
        }
        
        .bold {
            font-weight: bold;
        }
        
        .text-center {
            text-align: center;
        }
        
        .text-danger {
            color: var(--danger);
        }
        
        .mb-15 {
            margin-bottom: 15px;
        }
        
        .mb-20 {
            margin-bottom: 20px;
        }
        
        .mt-20 {
            margin-top: 20px;
        }
        
        .p-0 {
            padding: 0;
        }
        
        .segmented-control {
            display: flex;
            border: 1px solid var(--primary);
            border-radius: 8px;
            overflow: hidden;
            margin-left: 10px;
        }
        
        .segmented-control label {
            flex: 1;
            text-align: center;
            padding: 8px 12px;
            background-color: white;
            cursor: pointer;
            transition: background-color 0.2s;
        }
        
        .segmented-control input[type="radio"] {
            display: none;
        }
        
        .segmented-control input[type="radio"]:checked + label {
            background-color: var(--primary);
            color: white;
        }
        
        .saved-badge {
            background-color: var(--secondary);
            color: white;
            font-size: 0.7rem;
            padding: 2px 6px;
            border-radius: 10px;
            margin-left: 8px;
        }

/* Harmoniser le design du sélecteur Jour/Nuit avec les interrupteurs */
.segmented-control {
    display: inline-flex;
    align-items: center;
    border: 1px solid var(--medium-gray);
    border-radius: 34px;
    overflow: hidden;
    margin-left: 0; /* supprimer l'espace blanc à gauche */
}

.segmented-control label {
    padding: 8px 14px;
    line-height: 1;
    border-right: 1px solid var(--medium-gray);
}

.segmented-control label:last-of-type {
    border-right: none;
}

.form-group:has(.segmented-control) { 
    margin-bottom: 8px; /* évite un grand espace en bas */
}

/* Affichage radio stylé */
.segmented-control input[type="radio"] { display: none; }
.segmented-control input[type="radio"]:checked + label {
    background-color: var(--primary);
    color: #fff;
}

/* Petits boutons utilitaires */
.btn.btn-sm { padding: 6px 10px; font-size: .9rem; }